Game Points that Make Omaha Unique
While Texas Hold 'Em is the most popular poker variant in North America at the moment, there are a number of regions in Europe and other parts of the world where Omaha is a game enjoyed by a larger number of people than Hold 'Em. Many people say this is because of the many elements in the game that make Omaha unique while others say it just illustrates preferential differences between people living in Europe and people living in the United States.
Well, while it would be difficult to answer that specific question in the time allotted, let us take a look at some of the points that make the game of Omaha unique and let you draw your own judgement as to who is correct.

The first thing that makes omaha poker unique is the number of cards that are in play. At a 10-player Omaha table, no matter what else happens, 48 of the 52 cards in the deck will be used. Forty cards will be used to make the hands of the players, five cards will be used to make the community card board and three cards will be used as burn cards in the construction of the board.
There is no other common poker variant in which so much of the deck is used on such a regular basis. The closest would be seven card stud and even in that game all of the players need to go all the way to Seventh Street before that kind of usage is seen. The free flow of cards in Omaha means that a lot more hands get made in Omaha and therefore unless you are familiar with a player's maniac tendencies, you need to give strong bets a little more respect than you might otherwise be tempted to in Texas Hold 'Em.
Another major point to consider in the uniqueness of Omaha, as you might already know, is the requirement of two cards from your hand and three cards from the board making up your five card poker hand. This is something that makes the game unique and far more strategic in nature; something that a lot of Hold 'Em players fail to grasp initially. It is a conceptual leap to make and if you do nothing else in terms of getting yourself adjusted to Omaha, make sure that you drill this point into your head. It is the quintessential point of uniqueness about the game and the thing that makes it different from everything else.